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−87%per oz

SkinCeuticals · $150The Ordinary · $19.90

Shared: Acetyl hexapeptide-8, SYN-AKE dipeptide
The trade-off: It skips P-TIOX's 5% niacinamide and 5% PHA, so there is no exfoliating or tone-evening step, and The Ordinary doesn't publish its peptide percentages.
Sizes: 30 ml against 30 ml

SkinCeuticals P-TIOX Anti-Wrinkle Peptide Serum dupe

P-TIOX Anti-Wrinkle Peptide Serum costs about $150 for 30 ml ($147.87 / fl oz). The closest match below is The Ordinary Multi-Peptide + HA Serum at $19.90, about 87% less per ounce. Each pair is compared on format, finish and key ingredients, including what the dupe doesn't do.

Water-based serum for expression lines that pairs two peptides with 5% niacinamide and 5% PHA. SkinCeuticals reports softer lines across nine wrinkle types after 12 weeks; apply 4–6 drops after an antioxidant serum and before moisturizer.

Original: $150
Cheapest dupe: $19.90
You save: 87%

Prices checked 25 September 2026; Amazon's price today may differ.

Buy the $19.90 dupe See the original

The dupe, side by side

The original

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SkinCeuticals

P-TIOX Anti-Wrinkle Peptide Serum

$150

$147.87 / fl oz

−87%per oz

Cost per fl oz

SkinCeuticals$147.87 / fl oz

The Ordinary$19.62 / fl oz

$130.10 less at checkout than the original.

Size: Original · SkinCeuticals30 ml; Dupe · The Ordinary30 ml
Key ingredients: Original · SkinCeuticalsAcetyl hexapeptide-8, SYN-AKE dipeptide, 5% niacinamide, 5% PHA (gluconolactone); Dupe · The OrdinaryAcetyl hexapeptide-8, SYN-AKE dipeptide, Pentapeptide-18, Matrixyl 3000, Hyaluronic acid

What matches

Same two expression-line peptides as P-TIOX, acetyl hexapeptide-8 and the SYN-AKE dipeptide, plus pentapeptide-18 and Matrixyl collagen peptides in a water-based serum.

What the dupe does worse

It skips P-TIOX's 5% niacinamide and 5% PHA, so there is no exfoliating or tone-evening step, and The Ordinary doesn't publish its peptide percentages.

About the original Buy the dupe

Questions

What is the best dupe for SkinCeuticals P-TIOX Anti-Wrinkle Peptide Serum?

The Ordinary Multi-Peptide + HA Serum at about $19.90. Same two expression-line peptides as P-TIOX, acetyl hexapeptide-8 and the SYN-AKE dipeptide, plus pentapeptide-18 and Matrixyl collagen peptides in a water-based serum.

How much cheaper is The Ordinary Multi-Peptide + HA Serum than P-TIOX Anti-Wrinkle Peptide Serum?

P-TIOX Anti-Wrinkle Peptide Serum costs about $150 for 30 ml, or $147.87 / fl oz. The Ordinary Multi-Peptide + HA Serum works out at $19.62 / fl oz, roughly 87% less per ounce.

What does The Ordinary Multi-Peptide + HA Serum do worse than P-TIOX Anti-Wrinkle Peptide Serum?

It skips P-TIOX's 5% niacinamide and 5% PHA, so there is no exfoliating or tone-evening step, and The Ordinary doesn't publish its peptide percentages.